Wednesday, January 16, 2019

Extracorporeal Membrane Oxygenation for Failed TPA Therapy of Pulmonary Embolism: (ACR) - Lupine Publishers



Pulmonary embolism may cause cardiac arrest secondary to obstruction of blood flow. Traditional treatment strategies include anticoagulation, thrombolysis, and mechanical extraction. Some advocate for support with extra corporeal membrane oxygenation (ECMO); however, surgical therapies are contraindicated following thrombolytics. We describe the emergent use of peripheral ECMO following thrombolytic therapy for a saddle pulmonary embolism associated with multiple episodes of cardiac arrest. The patient was stabilized with peripheral ECMO, anticoagulated and subsequently weaned from ECMO without any major bleeding complications. The administration of thrombolytics should not be a contraindication for ECMO in patients with massive pulmonary embolism associated with hemodynamic instability.


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Wednesday, January 9, 2019

Cardiac Remodeling During the Morphogenesis of Neuroleptic Cardiomyopathy: (ACR) - Lupine Publishers

Cardiac Remodeling During the Morphogenesisof Neuroleptic Cardiomyopathy by Volkov VP in
Advancements in Cardiovascular Research (ACR) in Lupine Publishers 

Introduction: A neuroleptic cardiomyopathy NCMP belongs to secondary specific metabolic dilated cardiomyopathies. It is caused by side cardiotoxic effect of antipsychotic preparations. In its development NCMP passes three clinical stages: 1) latent, 2) developed and 3) terminal.
Aim: A morphometric study of the macroscopic heart condition in each clinical stage of NCMP
Material and methods: The autopsy protocols of 80 dead persons with NCMP in various stages and of 100 persons who did not have any accompanying cardiac pathology were studied. For analysis of the received data the original author’s method that we had developed for such studies was used.
Results: All macroscopic cardiac parameters in the case of NCMP statistically significantly differ from normal one, but no significant differences in various clinical stages of NCMP.
Conclusion: The process of cardiac remodeling on the organ level ends during the latent stage of the disease. Progression of myocardial dysfunction is connected with changes of myocardium microstructure.

https://lupinepublishers.com/cardiology-journal/fulltext/cardiac-remodeling-during-the-morphogenesis-of-neuroleptic-cardiomyopathy.ID.000115.php
http://lupinepublishers.com/acr/abstracts/cardiac-remodeling-during-the-morphogenesis-of-neuroleptic-cardiomyopathy.ID.000115.php
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Saturday, January 5, 2019

Acute Viral Myocarditis: The Role of Speckle Tracking Echocardiography: (ACR) - Lupine Publishers



Although, an accurate initial diagnosis of acute myocarditis can be challenging to make, all patients with suspected acute myocarditis need a thorough diagnostic work-up and undergo a full imaging evaluation from the very outset to rule out other condition with a similar clinical picture. An acute myocarditis and acute myocardial infarction may musgarate each other, as a result a thorough evaluation is warranted to be certain of the diagnosis, and these patients should be managed in a high cardiac care setting. The diagnosis of an acute myocarditis is based on symptoms, elevated markers of myocardial necrosis, electrocardiographic and imaging modalities including echocardiographic changes. A broad range of diagnostic tools are warranted during the initial diagnostic work-up, however a full echocardiographic evaluation should form an integral imaging modality to rule out other cardiac and systemic disorders, to properly evaluate ventricular function and presence of pericardial collections; and to further guide management.

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Interruption of the Aortic Arch in the Adult and Fulminant Myocarditis: A Strange Presentation

Introduction   53 years old female patient, who presented oppressive precordial pain, radiating to the neck and jaw, for which she went to...