Tuesday, December 11, 2018

Dynamics of Blood Pressure During the Development of Neuroleptic Cardiomyopathy: (ACR) - Lupine Publishers




The study of various clinic aspects of Neuroleptic Cardiomyopathy (NCMP) associated with the side cardiotoxic effect of Antipsychotics (AP) is actual. With the purpose to track dynamics of the Blood Pressure (BP) in the process of development of NCMP data about 78 died patients with schizophrenia (men - 53, women - 25) in whom NCMP is found on autopsy were retrospectively analyzed. At the age of 50 years were 43 persons, 44 died in the first stage of the disease, 12 - in the second one, 22 - in the third one. The conducted research allows to draw the following conclusions.


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Tuesday, December 4, 2018

Stimulus Propagation and Left Ventricular Torsion: (ACR) - Lupine Publishers


Introduction and objectives: The ventricular myocardium consists of a continuous muscular band. This anatomy would provide the interpretation for two fundamental aspects of left ventricular dynamics: the mechanism of left ventricular twist and rapid diastolic filling due to the suction effect. The aim of this study was to investigate the electrical activation of the endocardial and epicardial bands to understand ventricular twist and the mechanism of active suction during the diastolic isovolumic phase.

Methods: Five patients underwent three-dimensional endoepicardial electro anatomic mapping during ablation of lone atrial fibrilation or concealed epicardial accessory pathways.

Results: Three-dimensional endo-epicardial mapping demonstrates an electrical activation sequence in the area of the apex loop in agreement with the synchronic contraction of the descending and ascending band segments. The simultaneous and opposing radial activation of the ascending band segment, starting in the descending band segment, in the area in which both band segments intertwine, is consistent with the mechanism of ventricular twist. The late activation of the ascending band segment is consistent with its persistent contraction during the initial period of the isovolumic diastolic phase (the basis of the suction mechanism).

Conclusion: This study could explain the process of ventricular twist during systole and the active diastolic suction.


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Friday, November 30, 2018

Advocating the Need for a CT Coronary Angiography Screening Program for Prevention of Coronary Artery Disease in High – Risk Population & guiding future pharmaceutical research: (ACR) - Lupine Publishers




Cardio-vascular disease (CVD) is one of the major causes of morbidity and mortality in Europe and world. It accounts for majority of spend on healthcare in European Union countries and is the second on the list. Non-calcific plaques form the majority of plaques and non-calcific & mixed plaques are responsible for majority cases of severe stenosis. Since non-calcific and mixed plaques are resolvable by intensive statin therapy and are responsible for majority of severe acute coronary related events (vulnerable plaques), coronary artery disease is preventable if proper screening is done which should lead to significant decrease in economic burden of cardio-vascular & cerebro-vascular diseases. These findings warrant a discussion on systemic screening program for the same through CT coronary angiography.

Interruption of the Aortic Arch in the Adult and Fulminant Myocarditis: A Strange Presentation

Introduction   53 years old female patient, who presented oppressive precordial pain, radiating to the neck and jaw, for which she went to...